Oakland (4-10) are on a streak of four straight defeats whilst San Diego (7-7) is unbeaten in two. San Diego has faltered in the games that they were expected to win this season.
Mike McCoy and Dennis Allen won't need to give any motivational team talks on Sunday. Oakland will be keen repeat the early season victory over their rivals and restore some pride.
San Diego will be hoping for the win to hang on to their slim chance of an AFC wild card spot.
The Chargers are currently 38-56-2 against the Raiders.
San Diego is currently ranked 6th overall in total offense and Oakland is down in 18th place.
Ryan Mathews and Darren McFadden are both listed as questionable. Mathews has done a decent job in the San Diego offense. McFadden has made less of an impact for the visitors.
Here are my three bold predictions for the game.
Philip Rivers will put the Raiders to the sword.
Rivers has thrown for over 4,000 yards already. On Sunday he will have his fourth 400-yard game of the season.
Keenan Allen will show the NFL why he should be the rookie of the year.
Allen will have a career-high game with over 150 yards receiving.
Antonio Gates has still got it.
Gates will score two touchdowns and have a 100-yard game.
All eyes will be on the Raiders to see if they can eliminate the Chargers from the playoff picture. The Chargers may well be the favorites for this one but don't rule out the Raiders. In what has already been a strange season for the Chargers, they have failed to win what looks like the easy games on paper.
Bragging rights are on the line here for both teams.